koshlan.tetiana
Antibody development
STEP ONE
1.Determination of three-dimensional complex of the target protein with antibody flexible chain, which is subject to further modification. This should be at least one file with the extension of the PDB obtained by the method of X-ray diffraction analysis.
2.To control the received data, you can choose either of two options:
- you can use the additional structure of the PDB.
-take advantage of previously available data on the mutations performed, alanine scanning of one of the participants of the antibody-antigen complex
3.Our experts check files, adapt them for computational manipulations.
Antibody development
STEP ONE
1.Determination of three-dimensional complex of the target protein with antibody flexible chain, which is subject to further modification. This should be at least one file with the extension of the PDB obtained by the method of X-ray diffraction analysis.
2.To control the received data, you can choose either of two options:
- you can use the additional structure of the PDB.
-take advantage of previously available data on the mutations performed, alanine scanning of one of the participants of the antibody-antigen complex
3.Our experts check files, adapt them for computational manipulations.