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2019 GFP Second Place Winner: Movement of screw-propelled worms!

by Sumana Sundaramurthy and David Pruyne

 

A muscle’s function is accomplished by the sliding of strings that are

mainly made up of proteins called actin and myosin. These strings of

proteins are neatly arranged in rows inside a muscle cell and appear

as stripes under a microscope. We are trying to understand how

proteins called formins control the assembly of muscle proteins to

form such strings using the simple roundworm, Caenorhabditis

elegans as a model system. The image shows two worms expressing

muscle myosin tagged with GFP (green). They were stained with

phalloidin to visualize actin filaments (magenta) in muscles and also

with DAPI (blue) to visualize the nuclei.

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Uploaded on February 6, 2020