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2019 GFP First Place Winner: The assembly of a worm rocket!
by Sumana Sundaramurthy and David Pruyne
A muscle’s function is accomplished by the sliding of strings that are
mainly made up of proteins called actin and myosin. These strings of
proteins are neatly arranged in rows inside a muscle cell and appear
as stripes under a microscope. We are trying to understand how
proteins called formins control the assembly of muscle proteins to
form such strings using the simple roundworm, Caenorhabditis
elegans as a model system. The image shows a worm expressing
muscle myosin tagged with GFP (green). It is stained with phalloidin
to visualize actin filaments (magenta) in muscles and also with DAPI
(blue) to visualize the nuclei.
2019 GFP First Place Winner: The assembly of a worm rocket!
by Sumana Sundaramurthy and David Pruyne
A muscle’s function is accomplished by the sliding of strings that are
mainly made up of proteins called actin and myosin. These strings of
proteins are neatly arranged in rows inside a muscle cell and appear
as stripes under a microscope. We are trying to understand how
proteins called formins control the assembly of muscle proteins to
form such strings using the simple roundworm, Caenorhabditis
elegans as a model system. The image shows a worm expressing
muscle myosin tagged with GFP (green). It is stained with phalloidin
to visualize actin filaments (magenta) in muscles and also with DAPI
(blue) to visualize the nuclei.