puzzledpast
Figure 5
Substantia nigra lesions in Parkinsonism. Reproduction of some figures (plate 1, figs 1 and 2; plate III, fig 6; plate IV, figs 1,2 and 9) from Treitiakoff C. Etude de l'anatomie pathologique du locus niger de soemmering. Paris: Jouve, 1919. A-C: Topographic illustrations of the substantia nigra in a 80- year old patient suffering from senile dementia without signs of Parkinsonism (A), a patient who was afflicted by idiopathic Parkinson's disease (B), and a patient who suffered from post encephalitic Parkinsonism (C), as seen in the coronal plate. Note the marked loss of pigmental neurons in the two parkinsonian patients compared to the senile individual. (D) Microscopic depictions of nigral pigmented neurons undergoing "grumous" degeneration in parkinsonian patients. An unaffected neuron is shown in the upper left, whereas a neuron displaying signs of neurofibrillary fragmentation is depicted in the lower left. The neuron on the right is in a more advanced stage of degeneration and it exhibits Lewy bodies.
Figure 5
Substantia nigra lesions in Parkinsonism. Reproduction of some figures (plate 1, figs 1 and 2; plate III, fig 6; plate IV, figs 1,2 and 9) from Treitiakoff C. Etude de l'anatomie pathologique du locus niger de soemmering. Paris: Jouve, 1919. A-C: Topographic illustrations of the substantia nigra in a 80- year old patient suffering from senile dementia without signs of Parkinsonism (A), a patient who was afflicted by idiopathic Parkinson's disease (B), and a patient who suffered from post encephalitic Parkinsonism (C), as seen in the coronal plate. Note the marked loss of pigmental neurons in the two parkinsonian patients compared to the senile individual. (D) Microscopic depictions of nigral pigmented neurons undergoing "grumous" degeneration in parkinsonian patients. An unaffected neuron is shown in the upper left, whereas a neuron displaying signs of neurofibrillary fragmentation is depicted in the lower left. The neuron on the right is in a more advanced stage of degeneration and it exhibits Lewy bodies.