plosone-phylo
Figure 3
Phylogenetic analyses showing the unique status of plathyhelminth ?-integrins.Phylogram of the analysis of the full-length sequences of the S. mansoni ?-integrin receptor Sm?-Int1 and other ?-integrin receptors using CLUSTAL X (www.clustal.org) and TreeViewX. The phylogenetic relationship was deduced using the Bootstrap Neighbour-Joining (N?J) method and the bootstrap values were generated based on 1000 bootstrap trails with a random number generator seed of 100. Sequences were obtained from the National Centre for Biotechnology Information using the WWW Entrez Browser (www.ncbi.nlm.nih.gov), Swiss-Prot (www.uniprot.org), GeneDB (www.genedb.org), and the Schmidtea mediterranea Genome Database (smedgd.neuro.utah.edu/). The corresponding protein accession numbers are: Dm bPS (?-integrin PS, Drosophila melanogaster; P11584), Bg b (?-integrin, Biomphalaria glabrata; AF060203), Ce b-pat3 (?-integrin pat-3, Ceanorhabditis elegans; Q27874), Sp bL (?-integrin L subunit, Strongylocentrotus purpuratus; NP_999731), Sp bG (?-integrin G subunit, Strongylocentrotus purpuratus; NP_999732), Sp bC (?-integrin C subunit, Strongylocentrotus purpuratus; AF0559607), Mm b1 (?-integrin 1 receptor, Mus musculus; NP_034708.1), Rn b1 (?-integrin 1 receptor, Rattus norvegicus; NP_058718.2), Hs b1 (?-integrin 1 receptor, Homo sapiens; P05556), Gg b1 (?-integrin 1 receptor, Gallus gallus; NP_001034343.2), Xl b2 (?-integrin 2 receptor, Xenopus laevis; NP_001080017.1), Hs b2 (?-integrin 2 receptor, Homo sapiens; NP_000202.2), Hs b7 (?-integrin 7 receptor, Homo sapiens; NP_000880.1), HS b3 (?-integrin 3 receptor, Homo sapiens; P05106), Hs b5 (?-integrin 5 receptor, Homo sapiens; P18084), Hs b6 (?-integrin 6 receptor, Homo sapiens; P18564), Hs b 8 (?-integrin 8 receptor, Homo sapiens; P26012), Gc b (?-integrin receptor, Geodia cydonium; O97189), Am b (?-integrin, Acropora millepora; AF005356), Hs b4 (?-integrin 4 receptor, Homo sapiens; P16144), Sha b1 (?-integrin 1 receptor, S. haematobium; Sha_105750), Sm b1 (?-integrin 1 receptor, S. mansoni; FR749886), Sjp b1 (?-integrin 1 receptor, S. japonicum; Sjp_0081260), Cs b1 (?-integrin 1 receptor, Clonorchis sinesis; GAA31131.2), Em b1 (?-integrin 1 receptor, Echinococcus multilocularis; EmuJ_000528400), and Smed b1 (?-integrin 1 receptor, Schmidtea mediterranea; lcl|mk4.001280.01.01).
Figure 3
Phylogenetic analyses showing the unique status of plathyhelminth ?-integrins.Phylogram of the analysis of the full-length sequences of the S. mansoni ?-integrin receptor Sm?-Int1 and other ?-integrin receptors using CLUSTAL X (www.clustal.org) and TreeViewX. The phylogenetic relationship was deduced using the Bootstrap Neighbour-Joining (N?J) method and the bootstrap values were generated based on 1000 bootstrap trails with a random number generator seed of 100. Sequences were obtained from the National Centre for Biotechnology Information using the WWW Entrez Browser (www.ncbi.nlm.nih.gov), Swiss-Prot (www.uniprot.org), GeneDB (www.genedb.org), and the Schmidtea mediterranea Genome Database (smedgd.neuro.utah.edu/). The corresponding protein accession numbers are: Dm bPS (?-integrin PS, Drosophila melanogaster; P11584), Bg b (?-integrin, Biomphalaria glabrata; AF060203), Ce b-pat3 (?-integrin pat-3, Ceanorhabditis elegans; Q27874), Sp bL (?-integrin L subunit, Strongylocentrotus purpuratus; NP_999731), Sp bG (?-integrin G subunit, Strongylocentrotus purpuratus; NP_999732), Sp bC (?-integrin C subunit, Strongylocentrotus purpuratus; AF0559607), Mm b1 (?-integrin 1 receptor, Mus musculus; NP_034708.1), Rn b1 (?-integrin 1 receptor, Rattus norvegicus; NP_058718.2), Hs b1 (?-integrin 1 receptor, Homo sapiens; P05556), Gg b1 (?-integrin 1 receptor, Gallus gallus; NP_001034343.2), Xl b2 (?-integrin 2 receptor, Xenopus laevis; NP_001080017.1), Hs b2 (?-integrin 2 receptor, Homo sapiens; NP_000202.2), Hs b7 (?-integrin 7 receptor, Homo sapiens; NP_000880.1), HS b3 (?-integrin 3 receptor, Homo sapiens; P05106), Hs b5 (?-integrin 5 receptor, Homo sapiens; P18084), Hs b6 (?-integrin 6 receptor, Homo sapiens; P18564), Hs b 8 (?-integrin 8 receptor, Homo sapiens; P26012), Gc b (?-integrin receptor, Geodia cydonium; O97189), Am b (?-integrin, Acropora millepora; AF005356), Hs b4 (?-integrin 4 receptor, Homo sapiens; P16144), Sha b1 (?-integrin 1 receptor, S. haematobium; Sha_105750), Sm b1 (?-integrin 1 receptor, S. mansoni; FR749886), Sjp b1 (?-integrin 1 receptor, S. japonicum; Sjp_0081260), Cs b1 (?-integrin 1 receptor, Clonorchis sinesis; GAA31131.2), Em b1 (?-integrin 1 receptor, Echinococcus multilocularis; EmuJ_000528400), and Smed b1 (?-integrin 1 receptor, Schmidtea mediterranea; lcl|mk4.001280.01.01).