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mTOR-FKBP12-RAPAMYCIN

The mammalian TOR (mTOR) pathway integrates nutrient- and growth factor-derived signals to regulate growth, the process whereby cells accumulate mass and increase in size. mTOR is an atypical protein kinase which is frequently dysregulated in cancer and metabolic disorders. Rapamycin is an allosteric inhibitor of mTOR used as an immuno-suppressant. Feel free to use this image, just link to www.enzymlogic.com. Work done with the molecular visualization VMD program developed at the University of Illinois: www.ks.uiuc.edu/Research/vmd/

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Uploaded on September 13, 2013