The Game Changing Development Program seeks to identify and rapidly mature innovative/high impact capabilities and technologies for infusion in a broad array of future NASA missions. Multiple performing teams using varied approaches will attempt to achieve selected high impact challenge goals. Performing teams are held accountable for ensuring that discoveries move rapidly from the laboratory to application. The Game Changing Development Program portfolio will produce both subsystem/system level multidisciplinary innovations and component/discipline innovations. While advances in discipline and core knowledge are by-products of the Game Changing development Program, the objective is to mature transformational innovations for future space systems in preparation for flight demonstration.