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AMD Simulation

A simulation shows what the grocery store aisle looks like to someone with age-related macular degeneration (AMD). AMD damages the macula, a small spot near the center of the eye’s light-sensing retina. The macula lets us see objects that are straight ahead — it’s the part of the eye used for sharp, central vision.

NIH researchers from the National Eye Institute (NEI) profiling epigenomic changes in light-sensing mouse photoreceptors have a clearer picture of how age-related eye diseases may be linked to age-related changes in the regulation of gene expression. The findings, published online April 21, 2020 in Cell Reports, suggest that the epigenome could be targeted as a therapeutic strategy to prevent leading causes of vision loss, such as AMD.

Learn more: www.nih.gov/news-events/news-releases/nei-researchers-lin...

Credit: National Eye Institute, NIH

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Uploaded on September 13, 2020