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We’re not returning to ‘outdated’ predict and provide, says Robert Goodwill MP, Parliamentary under secretary of state for transport, the minister for roads and for cycling, too. He says this in a letter to Transport Xtra Magazine.
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I write following your coverage of the draft National Networks National Policy Statement (“Rethink ‘predict and provide’ roads policy, profession tells DfT” LTT 07 Mar).
The Government is not bringing in a programme of large-scale new road building, or working to an outdated “predict and provide” model. The draft National Policy Statement (NPS) very clearly rules this out. Our investment is foremost about improving the existing network, bringing forward schemes to improve the strategic road network where there is a strong justification based on economic benefits and quality of life, taking full account of environmental and social impacts. Almost 40% of the funding over this Parliament and next is for maintenance. Our investment in road improvements sits alongside huge investment that will transform our rail network, support sustainable transport choices and protect the environment, including supporting the uptake of ultra-low emission and electric vehicles.
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The letter Goodwill is referring to was packed with experts telling the Government they’re heading for disaster, if they build more roads. The experts included
transport planners, local authorities, and public transport and environmental lobby groups.
The draft NPS, on which consultation closed last week, predicts that road traffic will rise 42% in England between 2010 and 2040. This is the NPS that believes cycle use will drop, so won’t plan for cycling.
The Transport Planning Society says the road sections of the document are “one of the weakest policy statements of recent years”.
“Parts of the document dismiss key policy elements as simply irrelevant, including demand management and the use of sustainable modes. Land use planning, either to minimise the need to travel, or locate travel generators close to sustainable networks is completely missing.”
The Local Government Technical Advisers Group (TAG) calls for the statement to be totally rewritten. “So much is wrong with the starting point for this statement that it would be very damaging for the country and its people without a fresh start. The use of national traffic forecasts to continue (or revive) a policy of predict and provide is seriously flawed. The potential demand for increased travel is possibly true but a predict and provide model, even for trunk roads, is highly undesirable. It is deeply concerning that phrasing of the document belittles the benefits of investment in non-car based modes of transport,” says TAG.
The Chartered Institution of Highways and Transportation said: “CIHT does not think the document clearly establishes the need for development of the national networks, particularly on the road network. The potential for modal shift from road to rail for passengers is written off in simplistic terms, taking no account of regional and local variations. It does not address demand management in any detail.”
Dorset County Council says: “The outcome [of the NPS] is likely to be increased pressure on local roads, whilst local highway authorities are effectively starved of the funds that will be needed to resolve the resultant urban congestion. We do not think it sensible to devise an NPS that does not include strategies for the 98% of the road network outside Highways Agency control.”
On the other hand, motoring groups have welcomed the NPS. The RAC Foundation says it can find “little to disagree with” in the draft NPS.
www.transportxtra.com/magazines/local_transport_today/new...
Kenworth’s Predictive Cruise Control system becomes standard on the Kenworth T680 on-highway flagship beginning July 1, 2018. Kenworth Predictive Cruise Control combines GPS with cruise control to deliver enhanced fuel economy.
A krathong is small container or basket made of banana leaves, adorned with flowers, incense and candles. Loy Krathong means “to float a basket” which is what many people do during the festival on one of the three days.
The Thais see this as a time to wave goodbye to misfortune, wash away sins of the past year, and make wishes for the coming year. Often people will say a prayer before launching the krathong.
For the romantic at heart or young couples, Loi Krathong is the time to make a wish for happiness together. watching the route that a krathong takes is a popular way for couples to predict what the future holds for their relationship.
As a photographer, I was lucky to have access to a good vantage point to photograph people performing this yearly ritual.
I tried to capture the spirit of the event.
Investment pundits have been predicting the rise in price of silver for a while now. The white metal is expected to rise from its £11- £12 current spot price range in the near future. It could be an opportunity to build a sizeable stash of silver coins at the current price levels, allowing you to maximise the returns on your investment. But many investors are uncertain about the right coins to invest in. According to Daniel Fisher, founder and CEO of Physical Gold, one should never invest in obscure coins based on market conjecture. Well-known coins are a smarter choice simply because they enjoy a healthy secondary market and give you an opportunity to liquidate your investment when required within a short time span. One of the most well-known silver coins in the market is the silver Britannia.
The silver version was released by the Royal Mint after a decade of success enjoyed by the gold Britannia, which was released in 1987. The fame of the silver Britannia leapfrogged post 2013 after its purity rose to 99.9%. Coin investors don't always buy coins simply for the amount of silver that it contains. The motif and the design elements are of paramount importance to them. The silver Britannia is a winner on all these counts. Every edition of the silver Britannia portrays contemporary updated designs, which make all of these coins highly collectable.
A recent investor-focused informative video, released by Physical Gold about the silver Britannia is a great repository of information about the history, investment potential and attributes of this famous coin. In particular, the video emphasises the tax efficient nature of investments made in the silver Britannia. As legal tender in the UK, the coin enjoys a CGT free status which means profits that you make when selling your investments are tax-free up to a level. Physical Gold also sells the silver Britannia VAT free. The coin comes neatly packed into tubes of 25 or in monster boxes of 500.
There are fractional sizes of the coin available as well, which enhance divisibility in your portfolio. Reduced production costs ensure that the premiums you pay when buying the coins are kept to a minimum.
If you're a silver investor interested in putting your money on silver coins, do watch this video right away.
And so, as predicted, they nailed a wooden plank on the smashed window pane thus depriving our poor lot from the only sunlight we got in that section of the library. From now on, we'll need a flashlight to search for a book on the lower shelves...*sigh*
This afternoon I had to play the Ninja Librarian and drive out a bloke who was yelling - yes, YELLING - at his sweetheart: "JE T'AIME, MAIS SI, BON SANG, JE T'AIME" in the middle of the library. *rolls eyes*
I was paired with a chatterbox at the checkout, but I managed to finish "Narrow Dog to Carcassonne" by Terry Darlington. I enjoyed the book, even though I had to get used to the absence of quotation marks and the author isn't very kind to my country (I don't like Belgium. (...) The hole country has clearly come under control of aliens.)
I can't resist to share an excerpt with you:
Lucy, our eldest, rang at breakfast. Where are you? On the Rhône, down towards Avignon, I said. We are just getting ready to go through the Bollène lock, the second deepest in Europe. I am nervous, and your mother is nervous and we are being nasty to one another and we have made Jim [the whippet] nervous and he's whining. These locks are so big that one false step and you would never be found. Awful things happen on the Rhône. You don't know what has been going on here. We never know what to expect.
You know I just can't understand you, said Lucy. I was talking to Clifford about it and we really don't think it's good enough. I mean Cliff and I and Georgia gave you the best years of our lives. Whenever you needed us we were there. When you wanted advice we gave it, when your friends let you down we would comfort you. If you had bad luck in business or sport we would remind you what mattered was your own integrity, that bit of you inside that you know is good and no one can take away. We didn't ask for anything in return, only your love. And now we are getting old you leave us, you go off and do things against our advice. You don't care what we think any more. People ask Where are you, they have heard you are in trouble, and we say, We don't know, they probably are, they usually are. Grandmothers have evolved over millions of years so they can be back-up mothers, and grandfathers so they can put up shelves and build barbecues and give people money. Other grandparents babysit and tile their daughter's bathrooms but all you do is wander around and risk your lives and lavish your affection on a wretched dog that looks like a skeleton and steals things. You sit up drinking with people we don't know, dropouts and expats and bums and your grandchildren say Where are Granny and Grandad why can't they come to the pictures with us or take us to Chester Zoo and we say Last we heard they were being swept away down the bloody Rhône in a boat that was made for two feet of water with a dog that should be under the table in the Star or running around on the common chasing rabbits.
It was Lucy, I said, wishing us luck with the Bollène lock.
Today I attended the first day of the Predict Conference 2015 at the RDS. I will not be able to attend tomorrow but I hope to return on Thursday.
The on-going conference Conference (organised by industry-leader Creme Global) is an interactive meeting. It will, over three days, feature leading international thinkers in the areas of Data, Predictive Models, Technology and Decision making. At the meeting, we will be discussing the latest progress in Predictive Modelling and its future - from Data to Software and Hardware technology, plus Predictive Modelling methods and the best examples of Data-driven Decision-making.
Talks from leading entrepreneurs, data scientists, technologists, investors, and decision-makers (from business and government) will include case-studies and hands-on workshops. This conference has a focus on Data and Predictive Modelling technology like no other.
This photograph shows an aphasic stroke survivor looking at images of his MRI brain scan showing the area of his brain damaged by his stroke. The scan was taken as part of the Predicting Language Outcome and Recovery After Stroke (www.ucl.ac.uk/ploras) research study. This research is identifying the locations of stroke damage within the brain that determine the expected recovery of language. The stroke survivor in the image is coming ‘face to face’ with the location of his stroke damage, the MRI images in a sense both providing a window into the future and enabling him to come ‘face to face’ with his stroke at a biological and anatomical level. The study’s findings are being developed into a new clinical tool to ‘predict language outcome and recovery after stroke’ which should enable future aphasic stroke survivors to be given individual and accurate information about their recovery to help set rehabilitation goals.
Louise Lim (concept) Julie Guerin (Photography)
Tashiding Monastery is a Buddhist monastery of the Nyingma sect of Tibetan Buddhism in Western Sikkim, northeastern India. It is located on top of the hill rising between the Rathong chu and the Rangeet River, 40 kilometres from Gyalshing and 19 kilometres to the south east of Yuksam meaning Yuk-Lamas, Sam- Three in Lepcha Language which signifies the meeting place of three holy lamas from Tibet in 1641 A.D. Tashiding is the nearest town to the Tashiding Monastery (Gompa), which is the most sacred and holiest monasteries in Sikkim.
Tashiding means “The Devoted Central Glory” and the monastery by this name was founded in 1641 by Ngadak Sempa Chempo Phunshok Rigzing who belonged to the Nyingma sect of Tibetan Buddhism. Ngadak was one of the three wise men who held the consecration ceremony crowning the first King of Sikkim at Yuksom. It was extended and renovated in 1717 during the reign of the third Chogyal Chakdor Namgyal. 'Bhumchu Ceremony' or festival is a popular religious festival that is held on the 14th and 15th day of the first month of Tibetan Calendar.
The Tashiding Monastery is part of Buddhist religious pilgrimage circuit starting with the first monastery at Yuksam in Sikkim known as the Dubdi Monastery, Norbugang Chorten, Pemayangtse Monastery, the Rabdentse ruins, the Sanga Choeling Monastery, and the Khecheopalri Lake.
LEGEND
There are several legends linked to the most revered monastery and the Bhuchu festival that is held here.
According to one local legend Guru Padmasambhava shot an arrow into the air to select the place. Where the arrow he shot landed, he sat in meditation and that site eventually became the site of the Tashiding Monastery.
Another legend relates to the three monks who consecrated the first Chogyal of Sikkim at Yuksam. It is said that the three monks saw an unusual divine phenomenon of bright light shining on top of the Kanchendzonga mountain, which reflected to a site near the place where the present Tashiding Monastery has been built. Concurrently, a scented smell of incense followed by all pervading divine music was also noted. The first Chogyal who visited the site subsequent to hearing this unusual event, erected a small chorten at the site and named it as Thongwa-Rang-Grol. Legend further glorifies the site stating that a mere sight of it “confers self-emancipation”.
Another absorbing legend is related to the celebration of the Bhumchu festival at Tashiding Monastery. The legend is traced to the tantric art. Guru Padmasambhava, while teaching the tantric system of “Mahakarunika Avalokiteshvara Sadhana and initiation on emancipation from the cycle of mundane existence” to the King Trisong Duetsen, prince Murub Tsenpo, Yeshe Tsogyal and Verotsana in Tibet, sanctified the same holy vase with holy water, which is now kept in Tashiding Monastery and revered during the Bhumchu festival. This vase is made of five types prized jewels, divine soil and holy water said to have been gathered by Padmasambhava from religious centres in India, Odiuana and Zahor. The vase was made by the wrathful deity Damchen Gar-bgag and sanctified by Guru Padmasambhava himself by performing the “Sadhana of Yidam Chuchig Zhal (meaning tutelary deity of eleven heads)”. On this occasion, heavenly deities appeared in the sky and thereafter merged into the holy water contained in the vase. The vase then overflowed and the water dispersed in “all directions in the form of rays.” This ritual was immediately followed by an earthquake, which was considered an auspicious sign. The divine moment also witnessed the presence of the four guardian divinities namely, “the Gyalchen Dezhi/Cutur – Maharajika of Dharma and the gods of the thirty-three heavens (Samchu Tsasumgyi Lhanam) who showered flowers from the sky.” The event was witnessed by devotees and Padmasmabhava distributed the holy water from the vase to all assembled people, which spiritually benefited one and all. The vase was then hidden as a treasure under the care of the divine deities. However, the vase was rediscovered and passed through the hands of several holy men and finally placed at Tashiding by Terton Ngdag Sampachenpo. During the reign of the first ruler of Sikkim, Phuntshog Namgyal, the Terton recited the holy hymn “Om Mani Padme Hum” five billions when several unique events were also witnessed in Sikkim. After the religious ceremony the vase with the water has been kept on display in a small chamber in the Monastery under the custody of the Chogyal himself, which is opened once a year during the Bhumchu festival.
GEOGRAPHY
This monastery located at an altitude of 1465 m is built on top of a heart shaped hill or helmet shaped hill above the confluence of the Rathong Chu and Rangeet rivers, with the Mt. Kanchendzonga providing the scenic back drop. It is about 16 km from Yuksam, 40 km from Gezing via Legship.
The monastery is considered as the spiritual centre of Sikkim since it is encircled by many important monasteries in Sikkim in all directions such as: the Dubdi Monastery 23 km away on its northern direction, the Khecheopalri Lake (wish fulfilling lake) on the northwest, the Pemayangtse monastery on the west, the Shiva temple at Legship on the south, the Mongbrue gompa and Ravangla Bön monastery on the southeast, the Ravangla Gelug monastery on the east, the Karma Kagyud Ralang Monastery on the northeast.[citation needed] Gulia summarising the importance of this monastery has said:
For tashiding one can say: seeing is believing. The monastery is historically illustrious, geographically well located, aesthetically beautiful, spiritually divine – a place where nature and spirituality dwell together, urging the human race to be ecologically upright.
Geographically the Monastery and the Tashiding town are surrounded by four divine caves located in four cardinal directions. The four caves where Buddhist saints meditated are: On the East is the Sharchog Bephug, on the South is the Khandozangphu, in the West is Dechenpug cave and on the North is the Lhari Nyingphug. The main deity deified in the monastery is Tashiding and hence the monastery is also known as 'Dakkar Tashiding'.
HISTORY
In the 17th century, Ngadak Sempa Chemp built a small Lhakhang at this location. This was enlarged into the present monastery during the reign of Chogyal Chakdor Namgyal. Pedi Wangmo built the main monastery and installed many statues which are still seen in the monastery. Lhatsun Chenpo built the Chortens; which are considered holy. Yanchong Lodil, the Master craftsman crafted the flagstones that surround the monastery. These are carved with the holy Buddhist mantra 'Om Mane Padme Hum'.
ARCHITECTURE
An overall picture of the precincts of the monastery within the Tashiding town is provided in five distinct blocks namely, the Sinem market place, the outskirts, the main market place, the main Tashiding Monastery and the Chorten area.
The Sinek market place is located on an incline on the ridge between Rathong Chu and Rangeet River. There is a gompa here called the Sinolochu Gompa from where an approach leads to the Tashiding Monastery on the southern direction. The settlement is spread lengthwise and is 23 kilometres from Yuksom. A large 'Mani' stone is seen at the entrance to this settlement and the Tashiding market.
From the main market centre the approach to the Monastery is through a road, and also a foot path. The foot path in the southern direction has a gentle slope and passes through a Mani and then prayer wind wheels terminating at the entrance gate of the Monastery.
The Monastery itself consists of a 'Mani Lhakang' at the entrance surrounded by flags, and lead to the guest house. From this point ahead is the main 'Tashiding Gompa' which is called as Chogyal Lhakhang or the monastery, followed by the 'butter lamp house', four chortens, 'Tsenkhang', a new butter lamp house and finally terminating at the 'Guru Lhakhang', which is the temple of Guru Rinpoche. Other basic essential structures such as kitchen, school and residential housing are located on the left side of the approach path to the monastery.
In the 'Chorten area', there are 41 chortens categorised as 'Chortens of Enlightenment', 'Chortens of Reconciliation' and 'Chortens of Great Miracle', which are all of Rinpoches and Tathāgatas.
However, the main temple has undergone renovation work in modern times and rebuilt, but is still encircled by traditional buildings and chortens at the far end of the site, which holds the relics of Sikkim Chogyals and Lamas, including the 'Thong-Wa-rang-Dol' chorten which is believed to cleanse the soul of any person who looks at it.
Also of major note are the stone plates called the 'Mani', the work of Yanchong Lodil who inscribed them with the sacred Buddhist inscriptions, such as "Om Mane Padme Hum".
FESTIVALS
Bhumchu festival, which is linked by an ancient legend to Guru Padmasambhava, is about a divine vase filled with holy water kept in the monastery, which is opened for public display and worship every year on the night before the Full Moon day in the first month of Tibetan calendar. Bhumchu (Bhum=pot; Chu=water) is a Buddhist festival celebrated to predict the future. In this vase, water of Rathong chhu is stored for a year and kept in the Tashiding Monastery. It is opened during the festival by the lamas who inspect the water level and hence it is called the festival of holy water. The belief is that alteration in the quantity and quality of the water stored in the vase over a year would indicate the fortune of Sikkim and its people in the following year. If it is filled to the brim (which is interpreted as a measure of increase by 21 cups), the following year will be prosperous. If it is empty, famine will follow, and if it is half-filled also a prosperous year is predicted. If the water is polluted with dust it is interpreted as a sign of strife and clash. Once inspected and the Bhumchu festival is concluded, the lamas fill the vase with fresh water from the river and seal it for the opening in the following year.
The procedure followed for taking out the sacred water from the vase is that the first cup of sacred water is taken out for blessing the members of the Royal family of the Chogyals, then the second cup is meant for the Lamas and the third cup of water is meant for the devotees to whom it is distributed. Pilgrims come to the monastery from all regions of Sikkim to be blessed with the holy water. The festival is of particular importance to the Bhutias (ethnic Tibeteans) of Sikkim who hold the “life-sustaining water of the rivers” with great reverence. The festival falls on the 15th day Full Moon day of the first Tibetan month or Hindu month of Magh corresponding to February/March according to Gregorian calendar.
The basic purpose of the festival is to highlight the importance of water as a precious resource to be conserved and its purity preserved. The prophecy also sends a message to the people that waters should not be polluted and its environmental importance is propagated.
WIKIPEDIA
Heyyy.
So, I'm selling prints (of your choice). Prices are:
4x6=$2
5x7=$4
8x10=$6
If you are interested, just send me a message. :)
Les prédictions technologies, médias, télécommunications de Deloitte Canada à Montréal ont eu lieu le 19 janvier 2011.
www.youtube.com/user/DeloitteCanada#p/c/0899C16A89DAA853/...
Les Prédictions TMT 2011 de Deloitte sont les résultats de recherches, d'informations et de points de vue avant-gardistes en technologies, médias et télécommunications des quatre coins du Canada. « Les Prédictions de 2011 seront axées sur le thème global de la diversité, notamment pour tout ce qui touche à l'utilisation des différentes formes de médias, mais aussi aux plates-formes technologiques toujours plus nombreuses sur le marché », explique Robert Nardi, leader du groupe Technologies, médias et télécommunications de Deloitte à Montréal.
long time not doing videos, so thought id mix the 3 monsters together :)
honestly they do love each other :)
music by kaiser cheifs-i predict a riot :)
Trying to get pregnant? While conceiving requires a number of things to line up just so, you can take some of the guesswork out of it if you know how to track ovulation correctly. www.mamaxpert.com/blogs/post/how-to-track-ovulation
January 17, 1995, the Japanese city of Kobe was struck by a massive earthquake that devastated much of the city, killing over 5,500 people and injuring many thousands more. Shoko Asahara, the leader of the Japanese Aum Supreme Truth Aum Shinrikyo) sect, had surprisingly predicted, in a Tokyo radio broadcast on January 8. 1995, that a major earthquake would soon occur at Kobe. Asahara went even further and stated that this quake would be initiated by a "a foreign power" utilizing an electromagnetic (EM) weapons system.
Great night at London Predicts where we made our predictions for 2012. @tiredoflondon reads our predictions for the Olympics, Mayor Elections, Tube stuff, Diamond Jubilee and lots more. Thanks to Londonist for hosting the event.
Ryan Morhard, Project Lead, Global Health and Healthcare Industries, World Economic Forum, captured during the Session: Predicting and Forecasting Epidemics at the World Economic Forum - Annual Meeting of the New Champions in Dalian, People's Republic of China, July 2, 2019. Copyright by World Economic Forum / Ciaran McCrickard
This picture goes to show that it is near impossible to predict what will sell. In addition to dusting this one off for Erika Schlager, i remember that two of the girls in this shot bought this on the day of the event. They passed over action photos of themselves for this OOF lineup shot!
I had forgotten that i promised the Schlager's that i would give them the pictures i took of Erika at the final tournament of the season. In fact, i just received a couple orders from Norlanco parents-that was the only thing that reminded me of this. I thought i put these images behind me, but i guess i still have to edit a few of them before i put them in one of the archive hard drives (or in other words, the pit that never sees light of day)
Ryan Morhard, Project Lead, Global Health and Healthcare Industries, World Economic Forum, captured during the Session: Predicting and Forecasting Epidemics at the World Economic Forum - Annual Meeting of the New Champions in Dalian, People's Republic of China, July 2, 2019. Copyright by World Economic Forum / Ciaran McCrickard
With scientists predicting major climate changes on the horizon, Hollister Knowlton feels urgency about her work, but also hope.
She shares an analogy she's heard, that humanity is like a caterpillar that devours a tremendous amount. When it has eaten enough, spontaneously "imaginal cells" appear in its body. They are a relatively small number of cells, but somehow they migrate until they find one another. It is only when the imaginal cells reach a critical mass that the caterpillar is transformed into a pupa, the stage before becoming a butterfly.
~ The Wisdom to Know the Difference, by Eileen Flanagan
augustocuginotti.com/imaginal-cells-caterpillars-job-to-r...
My favorite metaphor for the current world transition, first pointed out to me by Norie Huddle (Butterfly, 1990), is that of a butterfly in metamorphosis.
It goes like this: A caterpillar crunches its way through its ecosystem, cutting a swath of destruction by eating as much as hundreds of times its weight in a day, until it is too bloated to continue and hangs itself up, its skin then hardening into a chrysalis.
Inside this chrysalis, deep in the caterpillar’s body, tiny things biologists call ‘imaginal disks’ begin to form. Not recognizing the newcomers, the caterpillar’s immune system snuffs them as they arise. But they keep coming faster and faster, then linking up with each other.
Eventually the caterpillar’s immune system fails from the stress and the disks become imaginal cells that build the butterfly by feeding on the soupy meltdown of the caterpillar’s body.
It took a long time for biologists to understand the reason for the immune system attack on the incipient butterfly cells, but eventually they discovered that the butterfly has its own unique genome, carried by the caterpillar, inherited from long ago in evolution, yet not part of it as such (Margulis & Sagan, Acquiring Genomes 2002).
If we see ourselves as imaginal discs working to build the butterfly of a better world, we will understand that we are launching a new ‘genome’ of values and practices to replace that of the current unsustainable system. We will also see how important it is to link with each other in the effort, to recognize how many different kinds of imaginal cells it will take to build a butterfly with all its capabilities and colors.
– Elisabet Sahtouris, Ph.D., evolution biologist, lecturer and author of EarthDance: Living Systems in Evolution
www.butterflymysteries.com/imaginal-cells.html
"The caterpillars new cells are called 'imaginal cells.' They resonate at a different frequency. They are so totally different from the caterpillar cells that his immune system thinks they are enemies...and gobbles them up--Chomp! Gulp! But these new imaginal cells continue to appear. More and more of them! Pretty soon, the caterpillar's immune system cannot destroy them fast enough. More and more of the imaginal cells survive. And then an amazing thing happens! The little tiny lonely imaginal cells start to clump together, into friendly little groups. They all resonate together at the same frequency, passing information from one to another. Then, after awhile, another amazing thing happens! The clumps of imaginal cells start to cluster together!.., A long string of clumping and clustering imaginal cell, all resonating at the same frequency, all passing information from one to another there inside the chrysalis."
How to predict the future with big data: Thomas Nørmark at TedxVennelystBlvd
In his talk Thomas Nørmark introduces us into the secret mechanisms of future predictions. This has nothing to do with fortune telling but patterns in big data. He illustrates how big data allows us to look into the future and even predict our individual future lives. He shows why you should see this inevitable development as an opportunity rather than a threat.
Thomas Nørmark is the head of innovation at itelligence Nordic. With his team he works on solutions using predictive analysis. He developed a “time machine” consisting of systems and solutions for predicting the future using social media data, object recognition and predictive analysis algorithms. One of his recent programs is to predict the movement of fish along Australia's coast. He hold a Master's degree in Computer Science from Aarhus University and gained extensive experience as SAP software consultant. When he was only nine years old, Thomas ran eight marathons and won bronze medal at The National Chess Championship.
Photo: Sugar Cube Studios & Greg McQueen: Photographer
NOAA’s Geostationary Operational Environmental Satellite-U (GOES-U) is offloaded from a C-5M Super Galaxy transport aircraft onto the flatbed of a heavy-lift truck at the Launch and Landing Facility at NASA’s Kennedy Space Center in Florida on Tuesday, Jan. 23, 2024. Crews transported the satellite to the Astrotech Space Operations facility in Titusville, Florida to prepare it for launch. Part of a collaborative NOAA and NASA program, GOES-U is the fourth in a series of four advanced geostationary weather satellites. Data from the GOES satellite constellation – consisting of the GOES-R, GOES-S, GOES-T and GOES-U spacecraft – enables forecasters to predict, observe, and track local weather events that affect public safety like thunderstorms, hurricanes, and wildfires. Photo credit: NASA/Leejay Lockhart NASA image use policy.
www.msn.com/en-us/health/medical/new-data-shows-mercks-ex...
New data shows Merck’s experimental covid-19 pill is less effective than early results predicted
Drugmaker Merck and its partner Ridgeback Biotherapeutics released data Friday showing their experimental pill to treat covid-19 is less effective than early clinical trials predicted, a finding that emerged as the Food and Drug Administration raised questions about the drug.
Molnupiravir, a pill that could be taken at home, had shown promise in cutting the risk of hospitalization and death by half among high-risk patients in data released by the company in October. But according to the latest findings Merck presented to the FDA, the pill reduced the risk of hospitalization and death only by 30 percent.
The study by the drugmakers found that, among participants receiving the pill, just one participant died during the trial, compared with nine deaths in the placebo group, the companies said in a news release Friday.
“It’s still a 30 percent effect, which is still good for a high-risk population,” said David Boulware, an infectious-disease physician and professor of medicine at the University of Minnesota Medical School who was not involved in Merck’s research. “It’s better than zero, and it’s a starting point, but it’s a little bit more modest.”
The FDA on Friday asked a panel of expert advisers to weigh the benefit of reduced hospitalizations and deaths in high-risk patients against potential risks associated with the drug. Because Merck and Ridgeback presented new clinical trial data to the agency after FDA scientists completed their review, regulators said their analysis may change ahead of a Tuesday meeting to consider the scientific evidence on the drug.
“The review issues and benefit/risk assessments may therefore differ from the original assessments provided in the briefing document which was based on the interim analysis,” an addendum to the FDA briefing materials said.
Merck and Ridgeback are seeking emergency-use authorization for their covid treatment, which would become the first easy-to-use pill to thwart the virus. The FDA advisory committee is expected to make a recommendation Tuesday, and agency officials typically follow the guidance of the advisers.
The agency reviewed data presented by the companies and determined that the clinical trial identified “no major safety concerns” related to adverse events. The most common side effects were mild-to-moderate diarrhea, nausea and dizziness. Still, the FDA identified several areas of concern, including potential risks for pregnant people and the possibility the drug could cause the coronavirus to mutate.
The FDA’s Antimicrobial Drugs Advisory Committee is scheduled to meet Tuesday to consider the scientific evidence on molnupiravir and weigh in on how the drug might safely be used to stave off severe infections.
The FDA could authorize the drug for use in treating patients at higher risk of hospitalization or death because of age or underlying health conditions such as obesity and heart disease. The agency’s review suggests that regulators may limit the drug’s use in people who are pregnant, hospitalized and vaccinated.
Merck’s pill works by interfering with an enzyme that the coronavirus needs to replicate itself and by changing the virus’s genome.
Unlike existing treatments — including monoclonal antibodies and the antiviral drug remdesivir — molnupiravir could be prescribed to patients and taken at home without a doctor’s direct supervision.
High-risk patients with covid-19 would start taking the pills within five days of developing symptoms and would continue using the drug twice a day for five days. The ease of use could make the treatment a powerful tool in preventing the worst outcomes by keeping mildly ill covid patients from getting worse and landing in the hospital.
While the drug could play a role in tamping down the toll of a pandemic that has killed more than 775,000 people in the United States, it is not a magic bullet. Some study participants, all of whom were unvaccinated and considered high-risk for serious infection, still ended up in the hospital with covid-related complications.
The FDA review suggests the pill will not be recommended for patients who are already sick enough to be hospitalized.
Because the medicine is not a perfect fix, experts have emphasized the continued need for people to get vaccinated to prevent serious covid infections.
The pill also carries potential risks, particularly for patients who are pregnant. Merck did not include in its clinical trial participants who were pregnant, and it required participants who could become pregnant to use birth control while taking the drug. That reflects concerns that the antiviral drug could disrupt the healthy development of a fetus because of the way it interferes with the virus’s genes.
The FDA proposed several ways to restrict the drug for pregnant patients because of the risk of birth defects and other potential problems.
“One approach is not to authorize [molnupiravir] for use during pregnancy because there are no clinical scenarios where the benefit outweighs the risk,” the agency’s review said.
A less restrictive approach would be to provide information about the risks and not recommend the pill during pregnancy, but allow doctors to prescribe the drug “at their discretion in certain clinical scenarios where the benefits were thought to outweigh the risks.”
Advisers to the FDA may also suggest precautions for women of childbearing age who take the drug, such as pregnancy tests and birth control.
Regulators also raised the question of whether vaccinated people should receive the pill. Because the vaccine offers robust protection against severe infection and death, the agency asked its advisers to evaluate whether vaccinated people would benefit sufficiently from the drug to justify the risks.
Merck’s pill was authorized for use in Britain this month for people older than 60 or with at least one risk factor for developing severe covid-19.
Regulators in the European Union gave member states the go-ahead to approve emergency use of the pill last week, as several countries in Europe contend with another wave of infections and enact new shutdown measures.
The FDA is expected to soon consider another antiviral pill — this one, Paxlovid, developed by Pfizer — after the company requested an emergency-use authorization last week. Pfizer’s drug, when taken within three days of symptoms, reduced the rate of death and hospitalization among high-risk patients by 89 percent, according to data from the company.
Jornada “Mejores prácticas en mantenimiento predictivo de transformadores” impartida en las instalaciones de IK4-TEKNIKER.
Más información en www.tekniker.es/es
Machines prédictives
Réseaux 2018/5 (n° 211)
www.cairn.info/revue-reseaux-2018-5.htm
Seul un article de ce n° de la revue “Réseaux“ est téléchargeable en PDF :
Machines à prédire
Bilel Benbouzid et Dominique Cardon
Dans Réseaux 2018/5 (n° 211), pages 9 à 33
Today is Doyo-Ushi-No-Hi (土用の丑の日) which translates to Midsummer Day of the Ox. It's commonly predicted as the hottest day of the year in Japan. I'm a Queenslander so I'm pretty used to this stinking hot and humid kind of summer. I certainly prefer it over the bone-chilling months of winter. But today, I have to admit, even put a tropical born and raised browny like me to the test.
The tradition on this day is to have some Unagi - grilled terikyaki eel. I love this stuff! So any reason to serve it up on the dinner table is good enough for me. This meal is meant to boost your energy to make it through this lethargic season. I'll have this through the winter months then… that's when my energy goes down to unhappy levels.
Cheers! Happy Eel Day.
Taken at 6:50 in the morning in France's Champagne-Ardennes region, after an unsuccessful attempt to photograph the landscape at sunrise.
Do you know a good way to predict the weather conditions when planning such outings?
Canon EOS 40D
EF-S17-85mm f/4-5.6 IS USM
70mm - 1/125 sec - f/5.6 - ISO320
Lightroom 5
The yacht Predictor og Wight, passes Gourock under sail and making good speed. She is a MURRAY 41 designed by Iain Murray and built by N.Harvey & D Heritage in the UK in 1996. Similar to the very sucessful Bashford Howison 41 by the same designer. Kevlar - Epoxy hull and deck construction. Alloy 3 spreader mast with runners and checkstays. Excellent race record. Top CHS/IR2000 racer. Professionally maintained and Dry Sailed. Twin wheel steering system, Carbon Rudder stock, laminated quadrant.
Sail no: GBR 9640R
LOA:12.49 m
LWL:11.89 m
Beam: 3.81 m
Draft: 2.60 m
Displacement:6,361 kg
Remsoft technology optimizes forest management and beyond: advanced analytics and predictive analytics resource management software provides capabilities of a decision model, decision support and optimization tool. Remsoft collaborative technology and linear programming software offers BI tools to optimize decisions in a complex world.
Jack Kostal
"Cognitive and Motivational Predictors of Academic Performance Under Stereotype Threat"
Senior
Psychology Major
The Creighton University College of Arts and Sciences Summer Research presentations by students who had received Dean's Scholarships for 2011.
For more information, see:
one of the wordier titles... but accurate. when you first experience loss a fog rolls into your head. it's our minds way of keeping us from dealing with the thought of the loss we've just experienced. also, your moods swing, you have no control... it's not our fault... it's just the way it goes. SOLD