Figure 6

Dendrogram based on primary protein sequence homology using the neighbor-joining method (applied to 1000 bootstrap data sets).Dendrogram depicting the phylogenetic relationship between the characterized five new polyol transporters (green arrows), the four cloned putative transporters with unknown substrate (gray arrows) and other members of the Sugar Porter family. Represented proteins (and corresponding accession numbers) are: AgMat1- Apium graveolens mannitol transporter (AAG43998.1); AtINT2- Arabidopsis thaliana inositol transporter 2 (CAJ00304.1); AtPmt1- A. thaliana polyol/monosaccharide transporter 1 (AEC06467.1); AtPmt2- A. thaliana polyol/monosaccharide transporter 2 (AEC06468.1); AtPmt5- A. thaliana polyol transporter 5 (NP_188513.1); CaItr1- C. albicans myo-inositol transporter 1 (XP_714885.1); CaHgt19- C. albicans potential myo-inositol transporter (XP_717819.1); CaStl1- C. albicans glycerol permease CaO19.5753 (XP_718089.1); CiGxs1- C. intermedia glucose/xylose/H+ symporter 1 (CAI44932.1); CiPlf1- C. intermedia putative lactose facilitator 1 (CAO79524.1); DEHA0D02167p- D. hansenii DEHA2D01474p hexose transporter (XP_458532.1); DEHA2B00528p- D. hansenii putative transporter (CAG84972.1); DEHA2C06380p- D. hansenii putative transporter (CAG86022.1); DEHA2E00726p- D. hansenii putative transporter (CAG87550.2); DEHA2F15444p- D. hansenii putative transporter (CAG89402.1); DhSgl1- D. hansenii galactitol/H+ symporter 1 (DEHA2E24310p; CAG88649.2); DhStl1- D. hansenii glycerol/H+ symporter 1 (DEHA2E01386p; CAG87598.2); DhSyi1- D. hansenii D-(+)-chiro-inositol/H+ symporter 1 (DEHA2G06490p; CAG90290.2); DhSyl1- D. hansenii sorbitol/mannitol/ribitol/arabitol/galactitol/H+ symporter 1 (DEHA2C05896p; CAR65543.1); DhSyl2- D. hansenii sorbitol/mannitol/ribitol/arabitol/H+ symporter 2 (DEHA2C05918p; CAG86001.1); DhXylHP- D. hansenii DEHA2C11374p hexose/xylose transporter (XP_458169.1); HbPlt2- Hevea brasiliensis putative polyol transporter protein 2 (CAP58707.1); KlLac12- Kluyveromyces lactis lactose permease (XP_452193.1); LjPlt4- Lotus japonicus putative polyol transporter protein 4 (CAJ29291.1); MdSot3- Malus domestica sorbitol transporter (BAD42343.1); PmPlt1- Plantago major polyol transporter (CAD58709.1); ScItr1- S. cerevisiae myo-inositol transporter 1 (DAA12329.1); ScItr2- S. cerevisiae myo-inositol transporter 2 (DAA10681.1); ScHxt1- S. cerevisiae hexose transporter 1 (DAA06789.1); ScHxt2- S. cerevisiae hexose transporter 2 (AAA34701.1); ScHxt3- S. cerevisiae hexose transporter 3 (DAA12185.1); ScHxt4- S. cerevisiae hexose transporter 4 (DAA06788.2); ScHxt5- S. cerevisiae hexose transporter 5 (DAA06790.1); ScHxt7- S. cerevisiae hexose transporter 7 (DAA12183.1); ScHxt9- S. cerevisiae hexose transporter 9 (NP_012316.1); ScMal11- S. cerevisiae maltose (alpha-glucoside) transporter (DAA08377.1); ScMph2- S. cerevisiae alpha-glucoside permease 2 (DAA11620.1); ScMph3- S. cerevisiae alpha-glucoside permease 3 (DAA08944.1); ScStl1- S. cerevisiae glycerol/H+ symporter 1 (DAA12366.1); SpItr1- Schizosaccharomyces pombe myo-inositol transporter 1 (CAA67211.1); SpItr2- Schi. pombe myo-inositol transporter 2 (NP_593320.1); SpaFsy1-S. pastorianus fructose/H+ symporter (CAC08232.1); SsLac1- Scheffersomyces stipitis lactose permease (XP_001383110.1); SsXut1- Sche. stipitis sugar transporter 1 (XP_001385583.1); SsXut3- Sche. stipitis sugar transporter 3 (XP_001387138.1); TdMal11- Torulaspora delbrueckii general alpha-glucoside permease (AAQ75121.1); ZrFsy1- Z. rouxii fructose/H+ symporter (ZYRO0C00374p; CAR26745.1).

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